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Research degrees

Research students are welcomed to àËÅöÊÓƵ as valued members of our thriving, research-intensive community. Find out more about in Brunel. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline.

Proposed PhD Projects

Description
Supervisor
Funding
Elucidating the mechanisms of early-stage breast cancer initiation
Using both transgenic cell lines and transgenic mouse models available in our research group, this project will determine the causal effects of increased accumulation of Reactive Oxygen Species (ROS) ...
Self Funded
Developing RAC1B-targeting therapies to improve the treatment outcomes for breast cancer
In this project, transgenic reporter cell lines, which will be generated using CRISPR-mediated gene editing, will be used to screen large drug libraries along with functional assays to analyse breast ...
Self Funded
Individual histone modification roles in regulation of transcription and cell decision-making
We are looking for a highly-motivated, technically-able and independent-thinking candidate to undertake a PhD project exploring the role of individual histone modifications in nuclear organisation, re...
Self Funded
Hypoxia-driven macrophage modulation in cancer and its impact on T cell immunotherapy
Hypoxia is a common feature of solid tumours. It presents a significant challenge to effective cancer treatment using immunotherapy. Macrophages are known to be recruited to hypoxic regions of the tum...
Self Funded
Development of a novel PCR-based assay to evaluate CAR-T safety using a human-based genotoxicity model
The project on offer is to develop a model for the evaluation of safety when using immunotherapy. CAR-T therapy is currently a novel approach to treat cancer using T cells infected by lentivirus vecto...
Self Funded
3D printing of scaffolds for tissue engineering and regenerative medicine
This project aims to develop multifunctional novel bioactive tissue scaffolds using 3D printing, biomaterials science and controlled drug delivery systems to enhance tissue regeneration. Tissue scaffo...
Self Funded
The role of PE/PPE proteins in tuberculosis
Tuberculosis remains one of the world’s biggest killers due to an infectious disease. There remains an urgent need for the development of effective vaccines and novel drug targets against the disease....
Self Funded
The effect on genome behaviour of growing cells in 3D matricies
There has been a small amount of evidence in the literature that growing cells in 3D scaffolds instead of 2D monolayers alters genome behaviour and organisation such that nuclear structure is altered ...
Self Funded
Machine learning approaches in health data science for risk prediction of cardiovascular diseases
Cardiovascular disease is killing over 17 million people in the world. almost a third of the death from cardiovascular diseases occur suddenly without prior signs and symptoms or diagnosis of any hear...
Self Funded
How do individual histone modifications help cells make decisions?
We are looking for a highly-motivated, independent-thinking candidate to undertake a PhD project exploring the role of individual histone modifications in nuclear organisation, regulation of transcrip...
Self Funded

 

Funding for doctoral studies

A number of studentships and other research funding opportunities are available at Brunel. Please see full list here: . 

Choosing your supervisor

Our researchers create knowledge and advance understanding, and equip versatile graduates with the confidence to apply what they have learnt for the benefit of society. Browse the list of the members of our Theme to select your potential supervisor here. You are welcome to approach your potential supervisor directly to discuss your research interests.

All research degrees are administered by the Postgraduate Programmes Office in Colleges. Once you have identified your area of research and a potential supervisor, please use the contact details provided for enquiries.